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Proteomics in Cancer Research Edited by Daniel C. Liebler Proteomics in CancerResearch covers both the basic principles of proteomics along with detailedpresentations of new and emerging technology that represent promisingbreakthroughs in cancer prevention and treatment. The topics covered include Basic concepts including setting up a proteomics laboratory massspectrometry protein separations protein array technologies and informaticstools Application of emerging technologies to proteomic analysis of cancercells and tissues including discussion of critical issues such ascharacteristics of cancer cell proteomes and proteinprotein interactions Application of proteomics approaches in clinical cancer research and a forecastof future research and applications In most cases applications of methods inbasic and translational cancer research that are discussed in the textrepresent the first uses of these proteomics approaches to study any disease.Critical issues that readers in cancer research need to understand are coveredin detail including Advantages and limitations of different technologies New approaches to the molecular classification of tumors Discovery of newbiomarkers and imaging targets and development of new proteomic platforms forprofiling and screening The unique proteomic features that characterize cancersoffer new opportunities for disease prevention and treatment. Despite intenseinterest however proteomics is just beginning to become a part of the cancerresearch mainstream as relatively few cancer researchers have training inproteomics methods and approaches. This book therefore is both a timely andan essential guide that will help readers understand key concepts of proteomicsand use its methods to search for ways to both cure and prevent cancer. «
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